Which breed is commonly predisposed to bladder cancer, particularly transitional cell carcinoma?

Scottish Terriers have a well-documented predisposition to bladder cancer, particularly transitional cell carcinoma (TCC). This breed consistently appears in studies and clinical observations highlighting an increased incidence of this malignancy compared to other breeds.

The anatomical and physiological characteristics of the Scottish Terrier may contribute to this heightened risk, possibly related to the breed's unique urinary tract anatomy or genetic factors that predispose them to neoplastic changes within the bladder. TCC typically arises from the transitional epithelium lining the urinary bladder, and certain breeds, including the Scottish Terrier, have been noted as more vulnerable due to inherited traits or predispositions.

Other breeds, such as the Beagle, Golden Retriever, and French Bulldog, have not demonstrated the same level of increased risk for bladder cancer specifically associated with TCC. While they may experience other health issues, they do not show the same behavioral or genetic indicators that correlate with an elevated incidence of this specific tumor type as seen in Scottish Terriers.